urO3 ozonated coconut oil suppositories are made from organic coconut oil, Vitamin E, and high purity ozone. Each PurO3 ozone suppository is 2.6 mL. They include fully ozonated oils created using a cold plasma ozone generator with medical oxygen. The benefit of using cold plasma (low frequency) ozone when producing ozonated oil is that no heat enters the oil. Traditional ozone generators (high frequency) produce heat upwards of 250 degrees which enters the oil and can cause it to lose some of its beneficial properties. Coconut is perfect for those who want more subtle levels of ozone and are often used for intimate moments, for dryness from menopause, and for irritation.