NeuEve AV Clear does NOT contain any antibiotics, toxins like boric acid, synthetic chemicals, hormones, drugs, herbs (such as black cohosh and wild yam), yeasts, bacteria, petroleum products, artificial color, artificial fragrance, and preservatives such as parabens. AV Clear (AV NIL) is the first self-care product designed to promote general wellness associated with AV. One pack has 3 suppositories. Based on customer feedback, most of them achieved a balanced microbiome by using 2-3 packs of AV Clear, while some said they experienced balance with 1 pack. When your discomforts are gone, you will know that you reach a balanced microbiome. A lab test can confirm if a healthy microbiome is achieved successful. If you have a lab test report and you want to know how to read it, you may find this article helpful. If AV is identified, this article shows you how to choose the right products for holistic healing and for maintenance to support the wellness. Here are the detailed instructions. If you want to find out if you need to take probiotics, you may find the answer in this article. For Best Results: * Add probiotics: https://help.neueve.com/kb/aerobic-vaginitis-av/to-clear-av-when-should-i-take-probiotics-to-be-most-beneficial * Add urinary tract health supplements : https://www.neueve.com/products/corsaria * Add yeast control supplements: Warning: Products may melt during shipping due to hot weather. Please refrigerate before use.