Patented Water and Fat Soluble The problem with regular CoQ10 supplements is that they do not dissolve in water and they dissolve poorly in fat, therefore, they are poorly absorbed by the body. NATURE TARGET® CoQ10 dietary supplement is different. NATURE TARGET® patented formulation dissolves in both water and adipose. NATURE TARGET® CoQ10 for Heart Health NATURE TARGET® CoQ10 is a good way to support heart health. Your heart, which needs a constant supply of energy, has the highest concentration of CoQ10 of all the tissues in your body.