ZYMOX Topical Hydrocortisone Cream1 oz Tube. ZYMOX Topical Spray for Hot Spots and Skin Infections 1 oz. Tube with .5% Hydorcortisone. The most common skin condition both dogs and cats can be afflicted with are hot spots. They are characterized by itchy, raw, sometimes bloody patches of skin. In addition to managing hot spots the ZYMOX topical spray is ideal in wound care as well as other common skin infections. Regardless if bacterial, fungal or yeast and they can be applied 1x/day as needed with no pre-cleaning or scrubbing of the skin because the LP3 Enzyme System reacts with the infectious pus and debris to form its antimicrobial properties. Pre- cleaning and cleaning during use disrupts this biological system and will negatively affect results. ZYMOX is safe, gentle and non-toxic and worry-free if a pet licks application site. Both contain hydrocortisone for inflammation relief.Recommended for use on wounds and the most troublesome skin infections.