Wholesale FRONTLINE Fast-acting flea & tick treatment for large dogs.

Protect your large dog with Frontline Plus, a trusted flea and tick treatment designed for dogs weighing 45–88 lbs. This 6-dose pack offers monthly, long-lasting, and fast-acting protection against adult fleas, ticks, flea eggs, larvae, lice, and mites. Formulated with two powerful ingredients—Fipronil (9.8%) and (S)-Methoprene (8.8%)—it breaks the flea life cycle and prevents future infestations. Waterproof 24 hours after application and easy to apply, Frontline Plus is safe for dogs 8 weeks and older. Just apply once a month for continuous protection.