10 million live probiotic microbes per ml help to protect your skin by competitive exclusion. This product comes in two parts … a glass vial that contains live probiotics (packed under nitrogen) and an 40ml glass spray bottle containing buffer solution and prebiotics. The vial is added before you first use the spray and the probiotics will stay alive for at least three months at room temperature. This product should be used in the mornings to protect your skin throughout the day.