PurO3 ozonated olive oil suppositories are made from organic, extra virgin olive oil and high purity ozone. Each PurO3 ozone suppository is 2.6 mL. They include fully ozonated oils created using a cold plasma ozone generator with medical oxygen. The benefit of using cold plasma (low frequency) ozone when producing ozonated oil is that no heat enters the oil. Traditional ozone generators (high frequency) produce heat upwards of 250 degrees which enters the oil and can cause it to lose some of its beneficial properties. Olive is in the middle of the scale and is ideal for those who don't want the amount of ozone hemp can hold or are specifically looking for a mid-range option.