NR (Nicotinamde Riboside) is the originalNAD+ boosting anti-ageing supplements that is an entirely natural compound found in our bodies. NR is a direct and potent NAD+ supplement. Increased NAD+ levels stimulate energy metabolism, DNA repair, and SIRTUIN activity. SIRTUINS are the longevity-genes shown to be active during caloric restriction and life-extension in many animal models.