CAS: 98-92-0 INCI: Niacinamide Chemical Structure: * Niacinamide, also known as nicotinamide or Vitamin B3, is an amide of niacin (nicotinic acid). * Its chemical structure includes a pyridine ring with an amide group. Physical Form: * Niacinamide is typically found as a white, crystalline powder. Function and Uses: * Skin Barrier Support: Niacinamide is known for its ability to strengthen the skin barrier, helping to retain moisture and protect against environmental stressors. * Anti-Inflammatory: It possesses anti-inflammatory properties, making it effective in calming and soothing irritated skin. * Hyperpigmentation Treatment: Niacinamide is known to inhibit the transfer of melanosomes (pigment-containing cells) to skin cells, making it beneficial for addressing hyperpigmentation and promoting an even skin tone. * Oil Balancing: It helps regulate sebum production, making it suitable for individuals with oily or acne-prone skin. Common Applications: * Niacinamide is a versatile ingredient found in various skincare products, including creams, serums, lotions, toners, and sunscreens. Benefits: * Moisture Retention: Niacinamide supports the skin's natural moisture barrier, reducing water loss and maintaining hydration. * Anti-Aging: It can improve the appearance of fine lines and wrinkles, contributing to a more youthful complexion. * Reduction of Redness: Niacinamide's anti-inflammatory properties help reduce redness and irritation in the skin. * Acne Management: It can be effective in managing acne by regulating oil production and reducing inflammation. Considerations: * Niacinamide is well-tolerated by most skin types and is considered non-sensitizing. * It is stable in various formulations and is compatible with other skincare ingredients. Regulatory Status: * Niacinamide is widely accepted and considered safe for use in cosmetics and skincare products when formulated according to regulatory guidelines. Usage Instructions: * Niacinamide is often incorporated into skincare products at concentrations ranging from 2% to 5%, depending on the specific formulation and desired benefits. * It can be used in both morning and evening skincare routines. Certificate of Analysis - Material Safety Data Sheet