Bio-Cellulose Face Mask - Patented Technology It is a mask sheet developed by microbial fermentation science. Bio-Cellulose technology was originally used by doctors to heal burns and wounds. Microbial Cellulose is inoculated with a strain of fruit juice which is a natural material made by cultivation and fermentation. It contains an organic compound that is the most abundant in the natural world. It is also called Fibrin, which accounts for more than 30% of all plant materials. It is a new material that can be applied to food, medicine, cosmetics, paper, industrial products, and textiles. The Bio-Cellulose mask also efficiently removes excess sebum.